av J Oras · 2016 · Citerat av 15 — Increased serum levels of the myocardial damage biomarker hsTnT, when measured early after onset of SAH, are independently associated
RESULTS: Of 882 patients with all biomarker results, 577 (65.4%) had detectable hsTnT levels ( LoD). Among the 305 patients (34.6%) with undetectable hsTnT,
14 Undetectable hsTnT was defined as values <5 ng/L, which is the limit of detection (LOD) of the current assay; detectable levels were defined as hsTnT ≥5 ng/L. hsTnT values between 5 and 14 ng/L were considered to be in the normal range. 2012-11-01 · The recently appeared high-sensitivity immunoassay to measure troponin T (hsTnT) has not yet been widely studied in the transplant population. We designed a cross-sectional study to evaluate hsTnT levels among 177 stable, asymptomatic patients, including 44.1% (78) males of overall mean age of 56.14 ± 14.25 years. hsTnT results and among US participants with an hsTnT level of at least 14 ng/L but a non-hsTnT level of less than 0.04 ng/mL (ie, threshold considered abnormal by manufacturer). Levels of HCY and hsTnT were natural logarithmically (Ln) transformed to normalize their distributions. The hsTnT was classified as detectable (≥3 pg/mL) or undetectable.
In a study of 202 patients with AHF, conventional cTnT and hsTnT assays were performed and patients were followed-up for >1 year for mortality. 37 Both cTnT and hsTnT had predictive value for death. In patients with a cTnT level <0.03 ng/ml, the addition of a positive hsTnT value, especially if greater than 20 pg 2018-08-31 Baseline NT‐proBNP and hsTnT levels were measured in the TIMI Clinical Trials Laboratory in 14 565 patients. Among the included patients, 9143 patients (62.8%) were male, 1464 (10.1%) had a history of heart failure and the mean age was 63.9 years. The median baseline NT‐proBNP and hsTnT levels were 75 … hsTNT level (P=.001), elevated Log ES (P=.03) as well as acute kidney injury (P<.001) and chronic obstructive pulmonary disease (COPD) (P=.039) emerged as independent prognostic parameters for adverse outcome. We also tested whether the Valve Aca-demic Research Consortium-2 (VARC- II) cutoff for myocardial damage (hsTNT peak The hsTnT level was significantly reduced in both groups. Interestingly, the hsTnT change was significantly greater in ischaemic HF than non‐ischaemic HF group (−42% vs.
Combination of baseline hsTnT levels with the sPESI allowed a more reliable identification of patients with a favorable long-term (6-month) prognosis (Figure 3, bottom, P<0.001; and Figure 4). Only 1 patient (0.8 [0.0–4.3]%) with a sPESI of 0 and hsTnT <14 pg/mL died within the 6-month follow-up period.
Previous studies indicate that the introduction of high-sensitivity troponin T (HsTnT) as a diagnostic tool for chest pain patients in the emergency department (ED) creates a high rate of false-positive tests. In the present study, we aimed to evaluate if the diagnostic performance of HsTnT for acute coronary syndrome (ACS) up to 3–4 h after presentation in elderly patients can be
However, the effect of statins on circulating hsTnT levels with moderate exercise is uncertain. Therefore, we evaluated the impact of statins on hsTnT level with moderate exercise. The hsTnT test has a higher degree of precision and sensitivity than the current TnI tests.
2013-01-15 · HsTnT levels had good discriminatory ability for prediction of abnormal SPECT-MPI (area under the curve: 0.739, 95% confidence interval: 0.609 to 0.868). Both reversible myocardial ischemia
Results w- ill be reported out with the following comment: Serum hsTnT levels were significantly higher in patients with cardiac amyloidosis than those with cardiac hypertrophy who were free of amyloidosis (cutoff value of 31 ng/L had a sensitivity and specificity of 74% and 76%, respectively). Measurements of TnT together with NT-proBNP and free light chains were shown to be useful in determining hsTnT stands for high sensitivity troponin T. Troponin T is a protein in the heart muscle which can be released into the blood when there is damage to the heart muscle as in a heart attack. hsTnT Reference Interval (males and females, age >1 year) <14 ng/L *Any result above the reference range will be flagged. For a baseline hsTnT (i.e.
None of these patients had adverse events. As shown in Table 2 , alone sPESI ≥ 1 point(s) had a higher sensitivity, and a higher negative predictive value for predicting a 30-day mortality in the present study.
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Interestingly, the hsTnT change was significantly greater in ischaemic HF than non‐ischaemic HF group (−42% vs.
We designed a cross-sectional study to evaluate hsTnT levels among 177 stable, asymptomatic patients, including 44.1% (78) males of overall mean age of 56.14 ± 14.25 years. hsTnT results and among US participants with an hsTnT level of at least 14 ng/L but a non-hsTnT level of less than 0.04 ng/mL (ie, threshold considered abnormal by manufacturer). Levels of HCY and hsTnT were natural logarithmically (Ln) transformed to normalize their distributions.
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By day 13, hsTnT continued to escalate to 1,728 ng/L despite CK levels which continued to fall to 295 units/L. The patient remained clinically asymptomatic and no
What happens if your troponin levels are too high (elevated)?; What diseases can This study was designed to determine the association between elevation of hsTnT level, MI and 30-day post-operative mortality after non-cardiac surgery (5).